[2] STL Blues 3-1 VGS Golden Knights [6] 2021-10-21 02:00
Stadium: T-Mobile Arena
Home Manager: Peter DeBoer Away Manager: Craig Berube
Head to Head
| NHL | 2021/05/09 02:00 | STL Blues v VGS Golden Knights | L | 1-4 |
| NHL | 2021/05/08 02:00 | STL Blues v VGS Golden Knights | L | 3-4 |
| NHL | 2021/04/08 01:00 | VGS Golden Knights v STL Blues | W | 1-3 |
| NHL | 2021/04/06 00:00 | VGS Golden Knights v STL Blues | L | 6-1 |
| NHL | 2021/03/23 02:00 | STL Blues v VGS Golden Knights | L | 1-5 |
| NHL | 2021/03/14 01:00 | VGS Golden Knights v STL Blues | L | 5-1 |
| NHL | 2021/03/13 01:00 | VGS Golden Knights v STL Blues | L | 5-4 |
| NHL | 2021/01/27 02:00 | STL Blues v VGS Golden Knights | W | 5-4 |
Home History
| NHL | 2021/10/19 02:00 | STL Blues v ARZ Coyotes | W | 7-4 |
| NHL | 2021/10/17 01:00 | STL Blues v COL Avalanche | W | 5-3 |
| NHL Pre-Season | 2021/10/09 00:00 | CLB Blue Jackets v STL Blues | W | 3-7 |
| NHL Pre-Season | 2021/10/07 00:00 | STL Blues v MIN Wild | L | 3-4 |
| NHL Pre-Season | 2021/10/06 00:00 | STL Blues v DAL Stars | L | 1-3 |
| NHL Pre-Season | 2021/10/03 00:00 | CHI Blackhawks v STL Blues | L | 5-1 |
| NHL Pre-Season | 2021/10/02 00:30 | STL Blues v CHI Blackhawks | W | 6-3 |
| NHL Pre-Season | 2021/09/29 23:00 | STL Blues v CLB Blue Jackets | L | 2-5 |
Away History
| NHL | 2021/10/15 02:30 | VGS Golden Knights v LA Kings | L | 2-6 |
| NHL | 2021/10/13 02:00 | SEA Kraken v VGS Golden Knights | W | 3-4 |
| NHL Pre-Season | 2021/10/10 00:00 | VGS Golden Knights v SJ Sharks | L | 0-4 |
| NHL Pre-Season | 2021/10/08 02:00 | ARZ Coyotes v VGS Golden Knights | L | 3-1 |
| NHL Pre-Season | 2021/10/06 01:00 | VGS Golden Knights v COL Avalanche | W | 7-4 |
| NHL Pre-Season | 2021/10/02 02:00 | LA Kings v VGS Golden Knights | W | 0-4 |
| NHL Pre-Season | 2021/10/01 02:00 | VGS Golden Knights v LA Kings | L | 1-3 |
| NHL Pre-Season | 2021/09/29 02:00 | COL Avalanche v VGS Golden Knights | W | 3-4 |