Stadium: Rupp Arena
Home Manager: John Calipari Away Manager: Tony Barbee
| NCAAB | 2021/11/24 00:00 | Central Michigan v Bellarmine | L | 69-76 |
| NCAAB | 2021/11/23 04:00 | Gonzaga v Central Michigan | L | 107-54 |
| NCAAB | 2021/11/16 01:00 | Central Michigan v Eastern Illinois | W | 62-61 |
| NCAAB | 2021/11/13 23:00 | Central Michigan v DePaul | L | 66-99 |
| NCAAB | 2021/11/10 01:00 | Central Michigan v Missouri | L | 68-78 |
| NCAAB | 2021/03/05 22:00 | Northern Illinois v Central Michigan | L | 79-74 |
| NCAAB | 2021/03/02 22:00 | Toledo v Central Michigan | W | 79-81 |
| NCAAB | 2021/02/27 18:00 | Central Michigan v Ball State | L | 91-97 |
| NCAAB | 2021/11/27 00:00 | North Florida v Kentucky | W | 52-86 |
| NCAAB | 2021/11/23 00:00 | Albany NY v Kentucky | W | 61-86 |
| NCAAB | 2021/11/20 00:00 | Ohio v Kentucky | W | 59-77 |
| NCAAB | 2021/11/17 00:00 | Mount St Marys v Kentucky | W | 55-80 |
| NCAAB | 2021/11/13 00:00 | Robert Morris v Kentucky | W | 60-100 |
| NCAAB | 2021/11/10 02:30 | Kentucky v Duke | L | 71-79 |
| NCAAB | 2021/03/11 17:00 | Mississippi State v Kentucky | L | 74-73 |
| NCAAB | 2021/03/06 17:00 | SC Gamecocks v Kentucky | W | 64-92 |