[94] Southern Illinois 31-24 Northwestern [1] 2022-09-17 16:00
Stadium: Ryan Field Round: 1
Home Manager: Pat Fitzgerald Away Manager: Nick Hill
Home History
| NCAAF | 2022/09/10 23:00 | SE Missouri St v SO Illinois | L | 34-31 |
| NCAAF | 2022/09/03 23:00 | SO Illinois v Incarnate Word | L | 29-64 |
| NCAAF | 2021/12/04 20:30 | SO Illinois v North Dakota State | L | 7-38 |
| NCAAF | 2021/11/27 23:00 | SO Illinois v South Dakota | W | 22-10 |
| NCAAF | 2021/11/20 18:00 | Youngstown State v SO Illinois | L | 35-18 |
| NCAAF | 2021/11/13 18:00 | SO Illinois v Indiana State | W | 47-21 |
| NCAAF | 2021/11/06 17:00 | Missouri St v SO Illinois | L | 38-28 |
| NCAAF | 2021/10/30 21:00 | SO Illinois v Northern Iowa | L | 16-23 |
Away History
| NCAAF | 2022/09/10 16:00 | Duke v Northwestern | L | 31-23 |
| NCAAF | 2022/08/27 16:30 | Northwestern v Nebraska | W | 31-28 |
| NCAAF | 2021/11/27 20:30 | Northwestern v Illinois | L | 14-47 |
| NCAAF | 2021/11/20 17:00 | Purdue v Northwestern | L | 32-14 |
| NCAAF | 2021/11/13 17:00 | Northwestern v Wisconsin | L | 7-35 |
| NCAAF | 2021/11/06 23:00 | Iowa v Northwestern | L | 17-12 |
| NCAAF | 2021/10/30 19:30 | Minnesota v Northwestern | L | 41-14 |
| NCAAF | 2021/10/23 16:00 | Northwestern v Michigan | L | 7-33 |