Stadium: Moda Center
Home Manager: Kyle Neptune Away Manager: T.J. Otzelberger
| NCAAB | 2022/11/20 23:00 | Wisc Milwaukee v Iowa State | W | 53-68 |
| NCAAB | 2022/11/13 18:00 | North Carolina A&T v Iowa State | W | 43-80 |
| NCAAB | 2022/11/08 01:00 | IUPUI v Iowa State | W | 39-88 |
| NCAAB | 2022/03/26 01:59 | Iowa State v Miami Florida | L | 56-70 |
| NCAAB | 2022/03/20 22:10 | Iowa State v Wisconsin | W | 54-49 |
| NCAAB | 2022/03/18 23:57 | Iowa State v LSU | W | 59-54 |
| NCAAB | 2022/03/11 02:30 | Iowa State v Texas Tech | L | 41-72 |
| NCAAB | 2022/03/05 23:00 | Iowa State v Baylor Bears | L | 68-75 |
| NCAAB | 2022/11/19 01:00 | Villanova v Michigan state | L | 71-73 |
| NCAAB | 2022/11/14 23:30 | Delaware State v Villanova | W | 50-60 |
| NCAAB | 2022/11/12 00:00 | Villanova v Temple | L | 64-68 |
| NCAAB | 2022/11/07 23:30 | La Salle v Villanova | W | 68-81 |
| NCAAB | 2022/04/02 22:09 | Villanova v Kansas | L | 65-81 |
| NCAAB | 2022/03/26 22:09 | Houston v Villanova | W | 44-50 |
| NCAAB | 2022/03/24 23:29 | Michigan v Villanova | W | 55-63 |
| NCAAB | 2022/03/20 18:40 | Ohio state v Villanova | W | 61-71 |