[22] Chicago Fire 1-0 Real Salt Lake [13] 2021-10-24 00:00
Stadium: Soldier Field
Referee: Rosendo Mendoza Home Manager: Raphael Wicky Away Manager: Pablo Mastroeni
Head to Head
| USA - MLS | 2019/06/23 00:00 | Chicago Fire v Real Salt Lake | D | 1-1 |
| USA - MLS | 2018/08/05 02:00 | Real Salt Lake v Chicago Fire | L | 2-1 |
| USA - MLS | 2017/03/11 19:00 | Chicago Fire v Real Salt Lake | W | 2-0 |
| USA - MLS | 2016/08/07 02:00 | Real Salt Lake v Chicago Fire | L | 3-1 |
| USA - MLS | 2015/05/09 19:00 | Chicago Fire v Real Salt Lake | L | 1-2 |