[3] Naomi Osaka 6-3,6-4 Serena Williams [11] 2021-02-18 03:00
Stadium: Rod Laver Arena Round: 28 Ground: Hardcourt outdoor
Head to Head
| A Day At The Drive | 2021/01/29 04:00 | Serena Williams v Naomi Osaka | 6-2,2-6,1-0 |
| WTA Toronto | 2019/08/09 23:00 | Serena Williams v Naomi Osaka | 6-3,6-4 |
| US Open - Kvinner | 2018/09/08 20:00 | Serena Williams v Naomi Osaka | 2-6,4-6 |
| WTA Miami | 2018/03/21 20:35 | Serena Williams v Naomi Osaka | 3-6,2-6 |
Home History
| Australian Open - Kvinner | 2021/02/16 01:30 | Su-Wei Hsieh v Naomi Osaka | 2-6,2-6 |
| Australian Open - Kvinner | 2021/02/14 00:00 | Garbine Muguruza v Naomi Osaka | 6-4,4-6,5-7 |
| Australian Open - Kvinner | 2021/02/12 04:05 | Ons Jabeur v Naomi Osaka | 3-6,2-6 |
| Australian Open - Kvinner | 2021/02/10 08:00 | Caroline Garcia v Naomi Osaka | 2-6,3-6 |
| Australian Open - Kvinner | 2021/02/08 00:00 | Anastasia Pavlyuchenkova v Naomi Osaka | 1-6,2-6 |
| WTA Gippsland Trophy | 2021/02/05 07:45 | Irina-Camelia Begu v Naomi Osaka | 5-7,1-6 |
| WTA Gippsland Trophy | 2021/02/03 00:00 | Katie Boulter v Naomi Osaka | 6-3,3-6,1-6 |
| WTA Gippsland Trophy | 2021/02/02 03:30 | Alize Cornet v Naomi Osaka | 2-6,2-6 |
Away History
| Australian Open - Kvinner | 2021/02/16 08:00 | Serena Williams v Simona Halep | 6-3,6-3 |
| Australian Open - Kvinner | 2021/02/14 02:15 | Aryna Sabalenka v Serena Williams | 4-6,6-2,4-6 |
| Australian Open - Kvinner | 2021/02/12 02:00 | Anastasia Potapova v Serena Williams | 6-7,2-6 |
| Australian Open - Kvinner | 2021/02/10 02:00 | Nina Stojanovic v Serena Williams | 3-6,0-6 |
| Australian Open - Kvinner | 2021/02/08 01:30 | Laura Siegemund v Serena Williams | 1-6,1-6 |
| WTA Yarra Valley Classic | 2021/02/05 02:20 | Danielle Rose Collins v Serena Williams | 2-6,6-4,6-10 |
| WTA Yarra Valley Classic | 2021/02/03 07:30 | Tsvetana Pironkova v Serena Williams | 1-6,4-6 |
| WTA Yarra Valley Classic | 2021/02/01 06:00 | Daria Saville v Serena Williams | 1-6,4-6 |